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| Researchers commonly define delayed secretory activation as occurring later than 72 hours postpartum. SSRI drugs are very helpful medications for many moms, so understanding and ameliorating difficulties moms experience can help them achieve their goals for breastfeeding their babies, said Horseman. More human research is needed before we can make specific recommendations regarding SSRI use during breastfeeding. Other researchers working on the study include: Aaron Marshall, Laura Hernandez and Karen Gregerson of the University of Cincinnati in Ohio; Laurie Nommsen-Rivers of Cincinnati Children's Hospital Medical Center in Ohio; Kathryn Dewey of the University of California at Davis; and Caroline Chantry of the University of California Davis Medical Center in Sacramento. The article, Serotonin transport and metabolism in the mammary gland modulates secretory activation and involution, will appear in the February 2010 issue of JCEM. Aaron Lohr The Endocrine Society About half of Medicaid-covered children and adolescents in Ohio who are in treatment for depression complete their first three months of prescribed antidepressants, and only one-fifth complete the recommended minimum six-month course of drugs to treat depression, new research suggests. Among those at the highest risk for not completing treatment are adolescents as opposed to younger children - and minority youths, particularly African Americans, according to the analysis of Medicaid prescription data over a three-year period.
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Optimal follow-up visits and adequacy of antidepressant dosing was associated with better adherence during both the acute and continuation phases of treatment. Though the study was conducted in Ohio, the findings are likely to have broad relevance to Medicaid-eligible children and adolescents across the United States who share similar problems affecting their access to quality mental health care, researchers say. There have been a lot of great advances in terms of medication and therapy interventions for depression. The best treatment is a combination of cognitive behavioral therapy and antidepressants, said Cynthia Fontanella, an assistant professor of social work and psychiatry at Ohio State University and lead author of the study. But there is a huge gap between the science and what is happening in the real world. And the gap is even greater for kids who live in poverty. The findings underscore the need for clinicians treating this population to deliver care according to guidelines established by the American Academy of Child and Adolescent Psychiatry, and to develop interventions that improve adherence in the most vulnerable groups, the study authors conclude.
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